Albert Science International Organization

ARTICLE DESCRIPTION: 

Swati Singh, Dharmendra Kumar Shrivastava, Yogendra Singh, Sunil Singh, Vishnu Kant Rai,^, Phytochemical investigations of acorus calamus plant extract and its study for antiulcer activity, ASIO Journal of Experimental Pharmacology & Clinical Research (ASIO-JEPCR), 2025, 8(1): 16-31.

Doi: 10.2016-37245516/;

https://doi-ds.org/doilink/09.2025-22636736/ASIO-JEPCR:2025/V8/I1/1041/SS

^1-4Shri Ramnath Singh Mahavidyalaya (Pharmacy), Gormi, Bhind (M.P.) – 477660, India

⁵Azad College of Education (Pharmacy), Sakha Janwara, Ghatampur, Kanpur Nagar, U.P., India

Abstract:

The condition known as ulcer occurs when the gastrointestinal mucosal defense and repair process is disrupted, resulting in erosion of the stomach or duodenal lining. These days, gastric hyperacidity and ulcers are increasingly frequent and cause a great deal of misery for people. There is an imbalance between the gastroduodenal mucosa's defense mechanisms and the lumen's harmful elements. The goal of this study was to determine the pharmacological properties of the Acorus calamus leaf extract. Petroleum ether and ethyl alcohol were used to extract the dry and powdered leaf material. The main goal of this research work was to carry out the preliminary phytochemical studies of ethanolic extract of leaves of Acorus calamus. Lastly, the antiulcer properties of an ethanolic extract of Acorus calamus leaves were further assessed. Ultimately, it may be said that the testing group that received greater dosages of the ethanolic extract of Acorus Calamus leaves may be showing some promise in treating ulcers when compared to the regular group. It may be possible to incorporate additional clinical data and proof from various studies to better validate this statement.

Keywords: Antiulcer Activity, Ethanolic Extract, Photochemical Screening, Acute toxicity studies, Histological Studies, Physicochemical Parameters.

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