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JOURNALS || ASIO Journal of Pharmaceutical & Herbal Medicines Research (ASIO-JPHMR) [ISSN: 2455-281X]
PATHOPHYSIOLOGY OF DIABETES: A REVIEW

Author Names : Sakshi Minocha
Page No. : 07-19  volume 3 issue 1
Article Overview

Abstract:

The ubiquity of diabetes is rapidly rising all over the globe at an alarming rate. Over the last three decades, the status of diabetes has been changed, earlier it was considered as a mild disorder of the elderly people. Now it becomes a major cause affecting the youth and middle aged people. Diabetes insipidus (DI) is a complex disease. It is inability of the body to conserve water. Polydipsia and polyuria are the major manifestations of DI. The proper management of DI is the replenishment of water loss. The best management for primary polydipsia is fluid restriction while fluid intake is used for adipsic diabetes insipidus.  Diabetes mellitus is an endocrinological or metabolic disorder with an increasing global prevalence and incidence. High blood glucose levels are symptom of diabetes mellitus. It is associated with metabolic complications that can subsequently lead to premature death.  The most disturbing trend is the shift in age of onset of diabetes to a younger age in the recent years. It is necessary to identify the diabetic patients at the earliest and provide appropriate lifestyle changes in preventing the onset of diabetes.

Keywords: polydipsia, insulin, glucose, Diabetes insipidus, polyuria.

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