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JOURNALS || ASIO Journal of Pharmaceutical & Herbal Medicines Research (ASIO-JPHMR) [ISSN: 2455-281X]
ASSAY OF HEPATOPROTECTIVE ACTIVITY OF CAMELLIA SINENSIS ON PARACETAMOL INDUCED LIVER TOXICITY
Author Names : Narwaria Urvesh Page No. : 01-03
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ARTICLE DESCRIPTION:
ARTICLE TYPE: RESEARCH
dids/doi No.:12.2015-77737978
dids link: http://dids.info/didslink/01.2016-54783958/
ABSTRACT:
The bioactive constituents from many plants are used as therapeutic agents against many physiological conditions. C. sinensis plant has many phyto-constituents like flavonoids, alkaloid and sterols. The present study appraised the hepatoprotective activity of methanolic extract of Camellia sinensis leaves against paracetamol-induced liver damage. Present activity was studied by assessing biochemical parameters such as alanine amino transferase (ALT), aspartate amino transferase (AST), bilirubin in serum. The results indicates that the extract was showed marked reduction in the level of marker enzymes and proves that C. sinensis having potent hepatoprotective activity.
Keywords: C. sinensis, hepatoprotective, phytochemical, AST, bilirubin
- Ariq AL and Reyaz AL. Phytochemical analysis of Camellia sinensis Leaves, Int. J. Drug Dev. & Res., October-December, 2012, 4(4):311-316.
- Ghosh P, Besra SE, Tripathi G, Mitra S, Vedasiromoni JR. Cytotoxic and apoptogenic effect of tea root extrat and two of its steroidal Saponin of TS1 and TS2 on human leukemic cell lines K562 and U937 and on cell of CML and all patients, Leuk Res, 30(4), 2006, 459-468.
- Chattopadhyay P, Besra SE, Gomes A, Das M, Sur P, Mitra S, Vedasiromoni JR. Anti inflammatory activity of tea (Camellia sinensis) root extract, Life sci, 74(15), 2004, 1839-1849.
- Shokrzadeh M, Ebadi AG, Mirshafiee SS, Choudhary MI, Effect of the aqueous green leaf extract of green tea on glucose level of rat, Pakistan journal of biological sciences , 9(14), 2006, 2708- 2711.
- Riso P, Erba D, Criscuoli F, Testolin G. Effect of green tea extract on DNA repair and oxidative damage due to H2O2 in Jurkat T cells, Nutr Res, 22(10), 2002, 1143–1150.
- Yoshida Y, Kiso M, Ngashima H, Goto T. Alterations in chemical constituents of tea shoots during its development, Chagyo Kenkyu Hokoku, 83, 1996, 9–16.